This article was going to talk about how sleeping pills work, from taking and how it’s going to react to your body and make you fall asleep that affects your brain.

These are the common questions how does sleeping will works?

When does this pill start to take effect?

What is T-max?

What is the relation with GABA?

So, let’s discuss all of these here and find out how these good night supplements help you getting fall asleep. We do know that sleep is essential to the human body and this is what we really need in our daily lives. We always know these since we were a child that you should be sleeping at least 8 hours of sleep. HOW DOES SLEEPING PILLS REALLY WORKS THIS TIME:

SLEEPING pills are known as Diphenhydramine – a commonly used the substance as Benadryl which is being utilized to treat allergies, nowadays, its been also prescribed as a treatment for people suffers from sleep disorders such as insomnia, sleep apnea and other kinds of disorder that makes them harder to get fall asleep.


GABA or Gamma-Aminobutyric acid is a natural amino acid inhibitory brain chemical that slows down the brain, – this chemical will slow you down blocking certain brain signals that lead to decreases nervous system activity. This compound can be found in fermented products such as yogurt, cheese, kimchi, sourdough, and pao cai, and it became more popular after it was developed into supplements that are widely used today because of its convenience and easy to take. Such as benzodiazepines, anti-anxiety drugs that will slows you down and make you calm and relax when anxiety triggers. These can be found in products such as Xanax and Klonopin.


This medication with FDA approval to treat insomnia that under the name of benzodiazepine receptor agonist (BZRA). 

This time let’s discuss benzodiazepine receptor agonist or called BZRA, this medication is FDA approved to treat insomnia, this chemical can be found in valium and Xanaxcommonly found in Tranquilizerone of the popular sleeping pills for insomnia. Receptor agonist activates some parts of the nerve cells in the brain which triggers you to fall asleep. The advantage of this medication is its fast reaction into your body, causing you to fall asleep in short-latency and duration, though the drawback of these pills is that you’ll become more dependent. It’s reported that it’s more likely to get harm to elder people, including symptoms like getting the risk to fall, such cases as accidents or vehicular accidents the reason is that they fall asleep, became more forgetful, and excessive daytime sleepiness. So, it is advised to take the medication as what is prescribed and follow the right protocol to avoid such hard into yourself.


Now, let us enumerate the sleeping pills available in the market, there are a total of 8 receptor agonist medication approved to treat insomnia and these are categorized as Benzos and Receptor Agonist;


  1. Estazolam (ProSom)
  2. Flurazepam (Dalmane)
  3. Quazepam (Doral)
  4. Temazepam (Restoril)
  5. Triazolam (Halcion)

Benzodiazepine Receptor Agonists

  1. Eszopiclone (Lunesta)
  2. Zaleplon (Sonata)
  3. Zolpidem (Ambien)

Both of these categories of Benzo have the same effects, but it only differs in brain activity according to half-life which the amount of time it takes to metabolize sometimes it takes around 1 – 120 hours before gets onset.

There are different amount half-life for every drug, and it varies on what supplement you were using, and all of this will slows down the effect and will measure out how long will it take to take the medication out on your system depends on how strong the medication you’ve been using with.


Of course, all of us want to have a shorter half-life kind of medication sleeping pills, because we don’t want to experience the withdrawal effect of it right? Usually, the effect is like having a hangover in the first thing you feel after you wake up.


Finally, let’s discuss the concept of T-max and the relation with the peak plasma concentration. Peak plasma concentration is determined whether the drug reaches the highest level of concentration usually happens when you take multiple dosages. Since we’re talking about sleeping pills the amount of dosage that enters your bloodstream after taking the pill. Your intake must have a shorter T-max in order to obtain the effectiveness of the medication with minimal side-effects, usually, it takes 1 to 2 hours to kick in.


Sleeping pills might be a very useful medication for those who struggle in getting into sleep, but proper medication should still be at least prioritized as it is the reason why you need this and why you need to stop indefinitely if things get worst. So do follow proper sleep hygiene, stop things that stimulate your brain, and sleep early.